POR indicates a reduction in quantity and quality of oocytes in women of reproductive age group. Early detection and active management are essential to minimize need for egg donation in these women. Diminishing ovarian reserve is a phenomenon often noted in women in their late to mid 30’s, but it may affect younger women as well. However, pregnancy rate remains low despite a plethora of interventions and is associated with high pregnancy loss.
Antral follicle count(AFC) and Antimullerian harmone(AMH) are the most sensitive markers of ovarian reserve identified to date and are ideal for planning personalized ovarian stimulation protocol.
Bologna criteria recommends the presence of a minimum of 2 of the following 3 for diagnosis of POR
1. Advanced maternal age (>40yrs)
2. A previous POR (Less than 3 oocytes with a conventional stimulation protocol)
3. An abnormal ORT (i,e AFC 5-7 or AMH 0.5-1.1 ng/ml)
Other than the age related decline, factors that may further deplete the ovarian reserve are endometrioma, pelvic infection, ovarian surgery / ovarian tumour or post CT RT for tumours.
We at GarbhaGudi feel that ovarian reserve testing should be offered to women who wish to delay childbearing and assist them in making informed decisions. AMH is being increasingly used as a tool to predict fertility potential of such women. They then have the choice of changing their priorities and decide not to delay conception or may undergo IVF to freeze eggs or embryos for future use (social freezing).
At present, there is no known mechanism to reduce the follicular atresia and prolong fertility. Social egg freezing is a step towards this but doesn’t always ensure pregnancy.
About GarbhaGudi:
GarbhaGudi is a chain of New-Generation Infertility Treatment Hospitals equipped with state-of- art-infrastructure & cutting-edge IVF Technology to address infertility issues & their emotional & mental effects on couples. We have a team of qualified & experienced doctors; their in-depth knowledge & expertise leaves no stone unturned to solve all your infertility issues. The Supportive & caring staff is always by your side to motivate & guide you throughout the journey. GarbhaGudi IVF, the best fertility treatment hospital in Bangalore, provides emotional support to couples facing infertility issues and sexual problems
For further details, you can also write to GarbhaGudi at dreams@garbhagudi.com or directly talk to our team at 8880000909