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What are PGD and PGS?

PGD and PGS

IVF technology has given a ray of hope to many couples enabling them to have their biological child. With cutting-edge techniques, advanced equipment, and dedicated lab personnel, the technology ensures better clinical results. A couple who undergoes fertility treatment such as IVF may have their fertility doctors advise to have their embryos undergo genetic testing before they get implanted into the uterus.

The two tests conducted on embryos for genetic defects are:

Preimplantation Genetic Screening (PGS)

After the tests, only the embryos free of genetic abnormalities get implanted in the uterus.

What is PGD?

PGD may be a sort of screening wont to detect genes linked to specific diseases. If either the man or the woman has a family history of a hereditary disease, this test can help ensure that the child born out of IVF will not have the condition. Either partner need not have the disease for the test to be conducted. In many cases, an individual could also be only a carrier of the gene.

Some of the diseases that PGD is employed to check for include:

  • Huntington’s Disease
  • Exchange of chromosomal material that may cause a miscarriage, mental retardation, or congenital anomaly
  • Marfan Syndrome
  • Cystic Fibrosis
  • Hemophilia
  • Duchenne Muscular Dystrophy
  • An abnormal number of chromosomes

What is PGS?

PGS test determines if an accurate number of chromosomes are present in the cells of the embryo. Normal, healthy humans have a complete of 23 pairs of chromosomes. IVF has a high risk of multiple pregnancies. Usually, 2-3 embryos are implanted within the uterus to maximize the probabilities of a successful pregnancy. PGS makes it possible to implant only a single embryo avoiding multiple pregnancies. Because having more or less than the usual number of chromosomes is one of the most common reasons why a fertilized egg fails to be implanted in the uterus and has miscarriages. Female aging increases the risk of abnormal chromosomes. Thus, this test is usually for women above 35 years and trying to have a family through IVF. The test is advisable if the woman has had recurrent miscarriages. PGS isn’t wont to test for specific diseases. As compared to the PGD test, this is often a way simple test. However, it can help to detect Down Syndrome. It happens by the presence of an extra chromosome in the person’s DNA. This screening may be helpful for gender selection.

What You Should Know about PGD and PGS

Both these tests use an amniotic fluid sample drawn on day three after the embryo culture. Withdrawing this sample risks the health of the fertilized egg & any damage to it will not result in a successful pregnancy. In addition, the PGS test requires samples for five to six embryos. In the case of older women, this might not be possible during a single IVF cycle. Hence, these women may require quite one IVF cycle to develop enough embryos for testing.

Therefore, it is crucial to work with a good fertility centre having expert doctors to undergo these tests only if required.

Which Test Do You Need?

Not all couples undergoing IVF need to take both tests. The test depends on many factors such as whether or not they have had earlier unsuccessful IVF cycles, past miscarriages, medical history, a family history of genetic diseases, etc. If you are looking to consult a Fertility Specialist, Call for a meeting or visit your nearest GarbhaGudi IVF Centre. Consult with the Nation’s finest Fertility & Reproductive Medicine Specialists.

Book An Appointment Now!

For further details, you can also write to GarbhaGudi at dreams@garbhagudi.com or directly talk to our team at 8880000909
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